Functional Medicine Clinics
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This is how Hashimoto’s Thyroiditis is managed in Functional Medicine Setting:
Testing - Conventional: TSH, free T4, anti-TPO antibodies, levothyroxine if hypothyroid
Functional medicine adds:
1. Full thyroid panel (TSH, FT4, FT3, rT3, anti-TPO, anti-TG) /2. Gluten sensitivity & celiac panel /3. Intestinal permeability test /4. Gut microbiome mapping /5. Adrenal function testing /6. Micronutrients (selenium, zinc, iron, vitamin D, B12) /7. Toxin exposure panel (perchlorates, fluoride, BPA) /8. Viral antibodies (EBV) /9. Omega-3 index /10. Oxidative stress markers
Possible root causes found:
Gluten sensitivity with leaky gut / Selenium/zinc deficiency / EBV reactivation / Chronic stress / Environmental toxins
Step-by-Step Treatment & Retesting
Weeks 0–6 (Immune Quieting & Gut Repair)
Maintain current thyroid hormone dose + Baseline full thyroid + nutrient + inflammation panel, gut permeability, EBV serology, toxin review + Strict gluten-free, remove dairy/soy if symptomatic + Protein-sufficient anti-inflammatory diet + Selenium 200 mcg/day, zinc 15–30 mg/day, vitamin D to 40–60 ng/mL, ferritin to 70-100 ng/mL + Gut repair: glutamine, zinc carnosine, digestive enzymes, targeted probiotic + Stress management & gentle exercise
Week 6–8 Retest
Symptom check (energy, hair, skin, temperature tolerance) + TSH, FT4, FT3; adjust thyroid hormone dose if necessary
If EBV reactivated: monolaurin, L-lysine, antiviral botanicals
Weeks 8–16 (Immune Modulation & Detox)
Continue GF diet, trial dairy/soy reintroduction later + Add myo-inositol 600 mg bid + Reduce toxins: filtered water, BPA-free storage, organic high-pesticide produce
+ NAC for glutathione support + Consider low-dose naltrexone (LDN) under supervision
Week 12–16 Retest
anti-TPO/anti-TG (target ≥30% drop in 3–6 mo)
CRP, vitamin D, ferritin
Final Retest (Weeks 24–36)
Goals: TSH 0.5–2.5, FT3 mid-optimal, antibodies trending down or <100 IU, symptoms
resolved
Maintenance: gluten-free long-term if antibody-responsive, maintain selenium/vitamin D,
annual thyroid US if nodules, labs every 6–12 mo
Relapse Protocol: strict elimination, stress-load reduction, short NAC course,
infection/toxin review
Key Lessons
1. Testing is both broad and deep — going beyond symptom confirmation to identify nutrient
gaps, hidden infections, environmental toxins, gut integrity, and metabolic patterns.
2. Treatment is staged — start with stabilization, then targeted repair, then
consolidation/maintenance.
3. Retesting is essential — every 6–8 weeks in active care to track biochemical and
symptom changes, with final retest marking readiness for maintenance.
4. Personalization matters — two patients with the same diagnosis may have completely
different root causes and treatment paths.
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